2009
32. Cai, S.; Li, Q.-S.; Fang, J.W.; Borchardt, R.T; Kuczera, K.; Middaugh, C.R.; and Schowen, R.L. The Rationale for Targeting the NAD/NADH Cofactor Binding Site of Parasitic S-Adenosyl-L-Homocysteine Hydrolase for the Design of Anti-Parasitic Drugs. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS. 28, 5-7, Special Issue, 485-503, 2009. 31. Li, Q.-S.; Cai, S.; Fang, J.W.; Borchardt, R.T; Kuczera, K.; Middaugh, C.R.; and Schowen, R.L. Evaluation of NAD(H) Analogues as Selective Inhibitors for Trypanosoma Cruzi S-Adenosylhomocysteine Hydrolase. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS. 28, 5-7, Special Issue, 473-484, 2009. 30. Liu S, Tang W, Fang J, Ren J, Li H, Xiao Z, Quarles LD. Novel regulators of Fgf23 expression and mineralization in Hyp bone. Mol Endocrinol. 2009 Sep;23(9):1505-18. Epub 2009 Jun 25.2008
28. Jiang L, Fang J, Moore DS, Gogichaeva NV, Galeva NA, Michaelis ML, Zaidi A. Age-associated changes in synaptic lipid raft proteins revealed by two-dimensional fluorescence difference gel electrophoresis. Neurobiol Aging. 2008 Dec 30. [Epub ahead of print] 27. Silva RA, Huang R, Morris J, Fang J, Gracheva EO, Ren G, Kontush A, Jerome WG, Rye KA, Davidson WS. Structure of apolipoprotein A-I in spherical high density lipoproteins of different sizes. Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12176-81. 26. Matthew R. Tubb, R. A. Gangani D. Silva, Jianwen Fang, Patrick Tso, and W. Sean Davidson. A three-dimensional homology model of lipid-free apolipoprotein A-IV using cross-linking and mass spectrometry. J. Biol. Chem. 283 (25), 17314-17323, 2008. 25. Chen. D.C.; Fang, J.W.; Yu, J.W. "Predicting Blood-Brain Barrier Penetration by Stochastic Discrimination". Proceedings of the 2008 International Conference on BioMedical Engineering and Informatics, BMEI 2008, May 28-30, 2008, Sanya, Hainan, China - Volume 1. IEEE Computer Society 2008. 24. Li, Q.-S.; Cai, S.; Fang, J.W.; Borchardt, R.T; Kuczera, K.; Middaugh, C.R.; and Schowen, R.L. "Comparative kinetics of cofactor association and dissociation for the human and trypanosomal S-adenosylhomocysteine hydrolases. 2. The role of helix 18 stability". Biochemistry. 47 (17), 4983-4991. 23. Fang, J. W.; Dong Y.H.; Williams, T.D.; Lushington G.H. "Feature selection in validating mass spectrometry database search results". Journal of Bioinformatics and Computational Biology. 6(1), 2008, 223-240. 22. Theerthama B.; L. Wang J.L.; Fang J.W.; and Lushington G.H. "Novel algorithms for the identification of biologically informative chemical diversity metrics". Current Computer-Aided Drug Design. Accepted. 21. Fang J.W.; Dong Y.H.; Salamat-miller N.; Middaugh C.R. DB-PABP: a database of polyanion-binding proteins. Nucleic Acids Research 36(Database-Issue): 303-306, 2008.2007
18. Fang, J.W.; Grzymala-Busse, J.W. "Predicting Penetration Across the Blood-Brain Barrier - a Rough Set Approach". Proceedings of 2007 IEEE International Conference on Granular Computing, IEEE Computer Society Press, pp. 231-236.
17. Sang Y, Teresa Ortega M, Rune K, Xiau W, Zhang G, Soulages JL, Lushington GH, Fang J.W., Williams TD, Blecha F, Melgarejo T. Canine cathelicidin (K9CATH): Gene cloning, expression, and biochemical activity of a novel pro-myeloid antimicrobial peptide. Dev Comp Immunol. 2007 Apr 16; [Epub ahead of print]
16. Wickstrum J.R.; Skredenske J.M.; Kolin A.; Jin D.J.; Fang, J.W.; Egan S.M. Transcription Activation by the DNA-Binding Domain of the AraC Family Protein RhaS in the Absence of its Effector-Binding Domain. Journal of Bacteriology. 189, 14, 4984-4993, 2007.
15. Fang, J. W.; Grzymala-Busse, J. W. “Mining Mass Spectrometry Database Search Results—A Rough Set Approach.” RSEISP 2007, LNAI 4585, pp. 340–349.
14. Fang J.W.; Salamat-miller N.; Dong Y.H.; Middaugh C.R. Prediction of Polyanion Binding Potential in Proteins Using Random Forest. Proceedings of BIOCOMP07, 427-431, June 25-28, 2007.
13. Hanzlik RP, Koen TM, Theertham B, Dong YH, and Fang J.W. The Reactive Metabolite Target Protein
Database - A Web-Accessible Resource. BMC Bioinformatics. 2007, 8:95.
12. Li, Q.-S.; Cai, S.; Borchardt, R.T; Fang, J.W.; Kuczera,
K.; Middaugh, C.R.; and Schowen, R.L. Comparative kinetics of cofactor association and dissociation for the human and trypanosomal S-adenosylhomocysteine hydrolases. 1. Basic features of the association and dissociation processes. Biochemistry, 46 (19), 5798 -5809, 2007.
11. Salamat-Miller, N.; Fang, J.W.; Seidel, C.; Smalter, A.;
Assenov, Y.; Albrechat, M.; Middaugh, C.R. A Network-Based Analysis of Polyanion Binding Proteins Utilizing Human Protein Arrays. J. Biol. Chem. 282, 14, 10153-10163, 2007.
10. Suprenant, K.A.; Nathan Bloom1, N.; Fang, J.W.; Lushington,
G.H. The Major Vault Protein is Related to the Toxic Anion Resistance Protein
(TELA) Family. J. Exp. Biol. 210, 946-955, 2007.
2006
9 . Salamat-Miller,
N. S.; Fang, J. W.; Seidel, C.; Smalter, A.; Assenov, Y.; Albrecht,
M.; Middaugh1, C. R. A Network-Based Analysis of Polyanion Binding Proteins
Utilizing Yeast Protein Arrays. Molecular and Cellular Proteomics, 5, 12, 2263-2278,
2006.
8. Rider, V.; Isuzugawa, K.; Twarog, M.; Jones, S.; Cameron, B.; Imakawa, K.; Fang, J. W. Progesterone Initiates Wnt-ß-Catenin Signaling
But Estradiol Is Required For Nuclear Activation and Synchronous Proliferation
of Rat Uterine Stromal Cells. J. Endocrinology, 191(3):537-48, 2006.
7. Fang, J. W.; Grzymala-Busse, J. W. “Leukemia Prediction
from Gene Expression Data: A Rough Set Approach.” Lecture Notes in Computer
Science: 4062, 758-765, 2006.
6. Fang, J. W.; Grzymala-Busse, J. W. “Mining of MicroRNA
Expression Data: A Rough Set Approach.” Lecture Notes in Computer Science:
4029, 899-908, 2006.
5. Fang, J. W.; Dong, Y. H.; Lushington, G. H.; Ye, Q. Z.;
Georg, G. I. “Support Vector Machines in HTS Data Mining: Type I MetAPs
Inhibition Study.” Journal of Biomolecular Screening 11 (2): 138-144,
2006.
4. Haasl, R. J.; Fang, J. W. “Mining protein-protein
interaction data.” Current Bioinformatics 1, 2: 197-205, 2006. (invited
review)
2005
3. Fang, J. W.; Haasl,
R. J.; Dong, Y. H.; Lushington, G. H. "Discover protein sequence signatures
from protein-protein interaction data" BMC Bioinformatics 6: 277, 2005.
2. R. A. Gangani D. Silva, George M. Hilliard, Jianwen Fang,
Stephen Macha and W. Sean Davidson. "A Three Dimensional Molecular Model of
Lipid-free Apolipoprotein A-I Determined by Cross-linking/Mass Spectrometry
and Sequence Threading", Biochemistry, 2005, 44: 2759-2769..
1. Marchin, M,, Kelly, P.T. and Fang, J.W.; "Tracker: continuous
HMMER and BLAST searching" Bioinformatics, 2005, 21, 388-389.
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